We study gene regulation in development and how gene activity is perturbed in diseases such as cancer. Using a combination of functional genomics, genetics and biochemistry, we study how transcription is influenced by cellular signaling and how gene expression interfaces with chromatin architecture and epigenetic features of the genome. We also use cutting-edge nascent RNA-sequencing methods to investigate the transcription of protein coding mRNAs and non-coding RNA species such as enhancer RNAs.


Congratulations Chad!

We are so proud of Chad and his absolutely beautiful thesis defense. Wow!

Best of luck in your postdoc at UC Berkeley!

Welcome Allison!

We are so happy to have Allison Siegenfeld join the group. She comes to us following a PhD from Harvard's Chemistry department in Brian Liau's lab!