Our long term goal is to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use a combination of genomics, genetics and biochemistry to study the dynamics of gene expression, with a focus on developmental and immune responsive systems.
Karen was recently interviewed by Jan Witkowski, while at the RNA control & regulation Symposium at Cold Spring Harbor Laboratories. She talks about our recent work on the Integrator complex!
If you want to read about this work, check out the preprint, or keep an eye out for it in Molecular Cell!