Lab Members

Principal Investigator

Karen Adelman

Harvard Medical School
BCMP, LHRRB Building, Room 201a
45 Shattuck St.
Boston, MA 02115
Email: karen_adelmanathms [dot] harvard [dot] edu (karen_adelman[at]hms[dot]harvard[dot]edu)

We aim to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use a combination of genomics, genetics and biochemistry to study the dynamics of gene expression, with a focus on developmental systems and cancer.

Postdoctoral Fellows

Apoorva Baluapuri

Apoorva_Baluapuriathms [dot] harvard [dot] edu (Apoorva_Baluapuri[at]hms[dot]harvard[dot]edu)

Apoorva earned his PhD at the Cancer Systems Biology Lab at University of Würzburg in 2021. In the Adelman lab he is interested in studying the mechanisms and modularity of gene regulation by the Integrator complex and applying these findings to cancer therapeutics. 

(Maria) Jessica Bruzzone

maria_bruzzoneathms [dot] harvard [dot] edu (maria_bruzzone[at]hms[dot]harvard[dot]edu)

Jessica is a post-doctoral fellow interested in understanding the mechanisms that govern co-transcriptional processes like RNAPII pausing and splicing.

Ryan Marina

Ryan_Marinaathms [dot] harvard [dot] edu (Ryan_Marina[at]hms[dot]harvard[dot]edu)

Ryan is a post-doctoral fellow in the lab investigating the crosstalk between nascent RNA transcription and cellular stress response. He is supported by a fellowship from the American Cancer Society.

Allison Siegenfeld

allison_siegenfeldathms [dot] harvard [dot] edu (allison_siegenfeld[at]hms[dot]harvard[dot]edu)

Allison is interested in how the epigenome and epitranscriptome affect transcription elongation.

Graduate Students

Christopher Avalos

christopheravalosatg [dot] harvard [dot] edu (christopheravalos[at]g[dot]harvard[dot]edu)

Christopher is a graduate student in the Biological and Biomedical Sciences (BBS) PhD program. He is interested in studying how components of the pre-mRNA splicing machinery are able to regulate transcription.

Shivani Bhandarkar

sbhandarkaratg [dot] harvard [dot] edu (sbhandarkar[at]g[dot]harvard[dot]edu)

Shivani is a graduate student in the Biological and Biomedical Sciences (BBS) PhD program and is co-mentored with Johannes Walter. She is interested in understanding the mechanisms of regulation by transcription factors.

Christy Goglia

cgogliaatg [dot] harvard [dot] edu (cgoglia[at]g[dot]harvard[dot]edu)

Christy is a graduate student in the Biological and Biomedical Sciences (BBS) PhD program.  She is interested in understanding processes that alter chromatin architecture and gene expression.     

Nikola Mizgier

nmizgieratg [dot] harvard [dot] edu (nmizgier[at]g[dot]harvard[dot]edu)

Nikola is a graduate student in the Biological and Biomedical Sciences (BBS) Program. She is interested in understanding the mechanisms that regulate the epigenetic landscape and transcription to inform efforts for therapeutic development. She is a nature lover and loves to paint.

Lab Manager

Emily Egan

Emily_Eganathms [dot] harvard [dot] edu (Emily_Egan[at]hms[dot]harvard[dot]edu)

Emily is a lab manager, working with the Adelman and Blacklow labs.

Research Assistants

Dalton McGlamery

Dalton_McGlameryathms [dot] harvard [dot] edu (Dalton_McGlamery[at]hms[dot]harvard[dot]edu)

Dalton is working to develop a cell-free system for the study of transcription and RNA processing. 

ChenCheng Zhao

ChenCheng_Zhaoathms [dot] harvard [dot] edu (ChenCheng_Zhao[at]hms[dot]harvard[dot]edu)

Chen has joined "Team Integrator" in the lab as a research assistant.

Alumni

Eileen Ablondi

Eileen defended her PhD in July 2022 and is now a freelance science writer. 

Piero Espinel

Piero is a graduate student in the Molecular Biosciences Program at The University of Kansas.

Emily Kaye

Emily joined Editas Medicine in August 2023, as part of their Platform Technology group.

Ben Martin

Ben recently left the lab to start his own group as an Assistant Professor at the Lady Davis Research Institute and Department of Oncology at McGill University. 

Karla Martinez Nevarez

Karla is a graduate student in the Biological and Biomedical Sciences (BBS) PhD Program. 

Claudia Mimoso

Claudia graduated in 2024 and is now an Independent Fellow in the Department of Genetics at the Yale School of Medicine.

Geoff Nelson

Geoff is now a Senior Scientist in Bioinformatics at AstraZeneca.

Chad Stein

Chad graduated in May 2023 and is now doing a postdoc at UC Berkeley.

Hanneke Vlaming

Hanneke moved back to the Netherlands in January 2023 to start her own lab at the University of Utrecht.