News
Claudia's paper on co-transcriptional splicing is out!
Co-transcriptional splicing regulates 3' end cleavage during mammalian erythropoiesis
Molecular Cell:
https://doi.org/10.1016/j.molcel.2020.12.018
Congratulations Claudia!
This important paper shows just how fast mammalian splicing can be, and demonstrates that splicing occurs without Pol II pausing near splice sites. Further, using long-read sequencing Claudia and Kirsten find that failure to splice an RNA molecule causes defects in 3' end formation.
A wonderful collaboration with Karla Neugebauer's lab!
IntS8-PP2A paper published in Molecular Cell!
Another Mol Cell paper out from our fantastic collaboration with the Wagner lab at UTMB. From our lab, David, Chad and Telmo were involved in this team effort.
Check out the paper here.